In lieu of the hundreds of thousands of adults that live with debilitating disease processes that affect the health of neurons, scientists continue researching new methods of treatment. Dr. Victor Castano and his team of scientists from the Centre of Applied Physics and Advanced Technology from the University of Mexico recently announced that they found a possible solution that can help seniors and their Sacramento, CA, Alzheimer’s caregivers live with cognitive disease.
Following six years of the trials and errors encountered during their research, Dr. Castano and his team bioengineered a nanogel that has been shown to encourage the regeneration of neurons in the brain. Nanogel was created using microscopic particles known as nanoparticles. The substance is biocompatible, which prevents attacks from the immune system and physical rejection. Scientists tested the gel using laboratory animals.
They successfully bypassed the blood-brain barrier so that the nanogel could enter the brain. Using laser tweezers externally, the researchers stimulated and manipulated the neurons bathed in the nanogel. The neurons responded favorably and began growing new healthy cells.
With the ability to track the nanogel once the substance enters the brain, the group of Mexican scientists believes that their invention could aid clinicians in getting a clearer view of brain activity during CT and MRI scans.
Researchers at Penn State developed a different method of regenerating neurons that sustained damage. The team explained that when neurons suffer injury or illness, glial cells arrive on the scene as first defense protection. However, the number of cells that congregate eventually transform into scar tissue.
The team hypothesized that the NeuroD1 protein that is commonly found in the hippocampus might solve the problem. Using deactivated retrovirus that contains the necessary protein, researchers injected the substance into the group of glial cells of laboratory mice. Within a week, the glial cells converted into normal neurons.
The testing also progressed to mature mice with cognitive problems similar to Alzheimer’s. Once again, the protein successfully converted the glial cells, which became part of the brain’s natural network. Once more research is conducted, it is possible that these treatments will give hope to Alzheimer’s, Parkinson’s, and dementia home care agencies in Sacramento in the coming years.
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